Tumor-associated macrophages derived CCL18 promotes metastasis in squamous cell carcinoma of the head and neck
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چکیده
منابع مشابه
Incidence of Etiologic Factors in Squamous Cell Carcinoma of Head and Neck in Ahvaz
Introduction: Squamous cell carcinoma (SCC) is the most common head and neck malignancy. Smoking, alcohol consumption, viral infections, exposure, oral hygiene, and dietary, genetic, and occupational factors are the most important etiologic factors. The aim of this study was determining the incidence of etiologic factors in head and neck SCC. Materials and Methods: This is a cross-sectiona...
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Background and Aim: Cutaneous squamous cell carcinoma (CSCC) is the second most common skin cancer. Mast cells may play a role in tumor progression and metastasis by increasing angiogenesis. The aim of this study was to investigate the role of mast cells by increasing angiogenesis in invasion of head and neck cutaneous squamous cell carcinoma. Materials and Methods: In this cross-sectional stud...
متن کاملJunB promotes cell invasion, migration and distant metastasis of head and neck squamous cell carcinoma
BACKGROUND While treatment failure in cases of head and neck squamous cell carcinoma (HNSCC) frequently takes the form of locoregional recurrences and distant metastasis, our understanding of the mechanisms of metastasis in HNSCC is limited. We initially performed the upstream and key nodes analysis together with whole gene microarray analysis characterized by distant metastatic potential in vi...
متن کاملMetastasis of Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and accounts for approximately 650,000 new diagnoses and 350,000 cancer deaths every year (Parkin, et al., 2005). In the United States, HNSCC accounts for approximately 5% of all cancer cases diagnosed per year. Even with significant advances in operative skills such as reconstructive microvascular free tiss...
متن کاملEpithelial-Mesenchymal Transition and Inflammation in Head and Neck Squamous Cell Carcinoma
Head and neck squamous cell carcinoma (HNSCC) represents a large majority of cancers arising from the head and neck, especially the oral cavity. Despite advances in therapy, the five-year survival rate remains low due to the number of patients presenting advanced stages of the disease. The role of epithelial-mesenchymal transition (EMT) in tumorigenesis in HNSCC remains unexplored. The current ...
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ژورنال
عنوان ژورنال: Cancer Cell International
سال: 2018
ISSN: 1475-2867
DOI: 10.1186/s12935-018-0620-1